In this episode, Dr. Gladden and nutrition expert Sarah Kennedy discuss Calocurb, a natural extract that uses evolutionary biology to suppress appetite. The discovery focuses on bitter taste receptors (T2Rs) located throughout the gastrointestinal tract, which historically served as a protective mechanism to slow the consumption of potentially toxic substances. By using a specific New Zealand hop extract, Calocurb triggers these receptors to signal the brain that the body is full. This process stimulates the natural release of satiety hormones—GLP-1, CCK, and PYY—effectively quieting "hunger noise" and reducing caloric intake without the need for synthetic pharmaceuticals.

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Takeaways

· Sarah Kennedy transitioned from veterinary medicine to nutrition.

· Calocurb is based on the hypothesis of appetite suppression through bitter taste receptors.

· Bitter taste receptors are present throughout the gastrointestinal tract.

· The primary hormones involved in appetite suppression are CCK, GLP-1, and PYY.

· Clinical studies showed an 18% reduction in calorie intake with Calocurb.

· Calocurb has a duration of action of four to six hours.

· 5% of users may experience a laxative effect as a side effect.

· The product can be used intermittently for weight management.

· Future research will explore the effects of Calocurb on adolescents and gut health.

· Calocurb is a natural alternative to synthetic appetite suppressants.

Chapters

00:00 Introduction to Calocurb and Sarah's Background

02:52 The Science Behind Appetite Suppression

05:56 Mechanisms of Action: Hormones and Receptors

08:55 Clinical Studies and Results of Calocurb

11:50 Long-term Effects and Usage Recommendations

14:57 Side Effects and Adaptation

17:57 Future Research and Development Plans

21:01 Conclusion and Where to Find Calocurb

To learn more about Sarah Kennedy:
Facebook: https://www.facebook.com/calocurbGLOBAL/
Instagram: https://www.instagram.com/calocurb
Website: www.calocurb.com

Reach out to us at: 

Website: https://gladdenlongevity.com/  
Facebook: https://www.facebook.com/Gladdenlongevity/ 
Instagram: https://www.instagram.com/gladdenlongevity/?hl=en  
LinkedIn: https://www.linkedin.com/company/gladdenlongevity 
YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw  

How Bitter Taste Receptors in Your Gut Can Instantly Kill Food Cravings - Episode 339

Gladden Longevity Podcast

How Bitter Taste Receptors in Your Gut Can Instantly Kill Food Cravings - Episode 339