21 Mar 2026
59m

Ep. 570 We’ve Been Wrong About Progesterone! – The Most Powerful Hormone for Heart, Brain & Longevity with Dr. Felice Gersh | Menopause & HRT

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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

The podcast explores the multifaceted role of progesterone beyond its traditional association with the uterus, emphasizing its significance in cardiovascular and neurological health. Dr. Felice Gersh, an integrative gynecologist, clarifies the historical context behind the misconception that progesterone is only necessary for women with a uterus, tracing it back to the use of synthetic progestins like medroxyprogesterone acetate (MPA) and the Women's Health Initiative (WHI). Progesterone is vital for nitric oxide production, endothelial function, and moderating sympathetic tone, impacting heart health and overall well-being. The conversation also covers factors accelerating ovarian aging, such as inflammation, environmental toxins, and sleep deprivation, highlighting the importance of lifestyle choices and mitochondrial health for women's longevity.

Outlines

Part 1: Basics, History

Part 2: Systemic Functions, Mechanisms

Part 3: WHI, Ovarian Aging

Part 4: Longevity, Applications

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