19 Mar 2026
1h 55m

Emily McDonald: Can You Rewire Your Brain?

Podcast cover

What Now? with Trevor Noah

The podcast explores the neuroscience of habits, addiction, and the power of mindset. Em, a neuroscientist, explains how dopamine drives habit formation, shifting from reward to anticipation, and how this relates to advertising's effectiveness. She details how maladaptive habits form and how rewiring the brain involves associating unwanted behaviors with disgust. The discussion covers the science behind visualization, meditation, and frequencies of sound, linking spirituality with neuroscience. Em shares her personal journey overcoming nicotine addiction and ADHD, emphasizing the importance of aligning one's self-concept with desired outcomes. The conversation touches on psychedelics, their impact on the default mode network, and their potential to alter self-perception, ultimately advocating for self-compassion and the power of internal dialogue.

Outlines

Part 1: Introduction, Background

Part 2: Mechanics of Addiction

Part 3: Science, Spirituality, Intuition

Part 4: Research, Studies, Application

Part 5: Focus, Stress, Performance

Part 6: Visualization, Resilience

Part 7: Relationships, Self-Concept

Part 8: Mindset, Belief, Writing

Part 9: Transformation, Conclusion

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