20 Feb 2026
30m

E309: Why Most VCs Firms will Die by 2030

Podcast cover

How I Invest with David Weisburd

The discussion centers on the future of AI and venture capital, particularly regarding agentic AI. Camilo Acosta, formerly a top AI engineer at Meta and now running Perceptive Ventures, shares insights on identifying investment opportunities that avoid competition with Big Tech. Acosta emphasizes that AI's core purpose is to replace human decision-making through prediction, judgment, and action, illustrated by examples like Waymo. He also addresses AI's potential to disrupt industries and create new job opportunities, highlighting that less regulated sectors will experience faster change. Acosta stresses the importance of a strong LP network and using AI to model successful founder traits, noting that the best founders often possess a level of ruthlessness needed to build transformative companies. The conversation also explores the shift towards audio-based interfaces as the future of computing platforms.

Outlines

Part 1: Background, Agentic AI Definition

Part 2: Investment Thesis, Market Strategy

Part 3: VC Operations, Fundraising

Part 4: Founder Psychology, Leadership Traits

Part 5: Future Outlook, Career Advice

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