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In this episode of Denatured, Jennifer C. Smith-Parker speaks to Erik Digman Wiklud, CEO of Circio and Jacob Becraft, CO-founder and CEO of Strand Therapeutics.

Since the mRNA vaccine breakthroughs of the COVID-19 era, attention has turned to what's next for programmable medicines. While first- generation mRNA prove the power of transient genetic instruction, its instability, immune reactivity, and short-lived expression have limited its use mainly to vaccines. Emerging platforms like circular and logic circuit RNA are expanding the field's therapeutic horizons.

Host

Jennifer Smith-Parker, Director of Insights, BioSpace

Guests

Erik Digman Wiklund⁠, CEO, Circio

Jacob Becraft, Co-founder and CEO, Strand Therapeutics

Programmable RNA 2.0: Beyond the First mRNA Revolution

BioSpace

Programmable RNA 2.0: Beyond the First mRNA Revolution