05 Feb 2026
2h 5m

Cognitive Decline Expert: The Disease That Starts in Your 30s but Kills You in Your 70s

Podcast cover

The Diary Of A CEO with Steven Bartlett

The podcast explores the critical role of exercise and lifestyle choices in preventing Alzheimer's disease, particularly in women. It highlights that Alzheimer's, often starting in one's 30s, is largely preventable through lifestyle adjustments rather than genetics. The discussion emphasizes resistance training, especially for leg strength, and high-intensity aerobic activity to enhance cognitive reserve and cardiovascular health. It cautions against excessive social media use due to its reliance on short dopamine hits, and advocates for handwriting and reading to preserve cognitive functions. The guest underscores the importance of monitoring blood pressure and considering hormone replacement therapy for women during perimenopause to mitigate brain glucose metabolism decline. Creatine supplementation is also recommended for its neuroprotective and energy-boosting benefits.

Outlines

Part 1: Alzheimer's Basics and Brain Health

Part 2: Physical Training for Cognitive Longevity

Part 3: Hormones, Biology, and Women's Health

Part 4: Sleep, Supplements, and Nutrition

Part 5: Testing, Willpower, and Cognitive Function

Part 6: Personal Mission and Reflections

Part 7: Closing

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