In this episode of PICU DOC on Call, Dr. Rahul Damania and Dr. Pradip Kamat discuss the resurgence of measles in the United States. They explore the virus's pathophysiology, clinical features, diagnostic methods, treatment options, and complications. They emphasize the critical role of vaccination in preventing measles outbreaks and address the historical context and public health challenges related to vaccine hesitancy. The speakers highlight the severe complications of measles, especially in immunocompromised patients, and advocate for robust vaccination efforts to protect vulnerable populations and prevent the spread of this preventable disease. Tune in to hear more!

Show Highlights:

Resurgence of measles in the United States
Historical context of measles outbreaks and vaccination impact
Current statistics and recent cases of measles
Pathophysiology of the measles virus
Clinical features and progression of measles infection
Diagnostic approaches for confirming measles
Differential diagnosis considerations for fever and rash
Treatment options and the role of vaccination
Complications associated with measles, including severe outcomes
Public health challenges related to vaccine hesitancy and advocacy for immunization

Resources:

CDC Measles Info Page

WHO Measles Global Surveillance

References:

Fuhrman & Zimmerman. Textbook of Pediatric Critical Care, Ch. 52

Long S et al. Principles and Practice of Pediatric Infectious Diseases, Ch. 227

Moss WJ. Measles. Lancet. 2017;390(10111):2490-2502

Paules CI, Marston HD, Fauci AS. NEJM. 2019;380(23):2185-2187

Measly Business - A Guide for the Pediatric Intensivist

PICU Doc On Call

Measly Business - A Guide for the Pediatric Intensivist