30 Jan 2026
1h 4m

The Nobel Prize Molecule That Nearly Doubles Lifespan : 1407

Podcast cover

The Human Upgrade: Biohacking for Longevity & Performance

The longevity and mitochondrial function benefits of C60, particularly ESS-60, are examined, with Chris Burres, the original manufacturer of the molecule, as the guest. Discussion points include the molecule's unique electrical properties, its potential for life extension based on rat studies showing a 90% increase in lifespan, and its role as a selective antioxidant. Burres details ESS-60's ability to buffer oxidative stress within mitochondria by capturing negatively charged reactive oxygen species, preventing cellular damage. Personal anecdotes and clinical observations suggest improvements in mental focus, sleep quality, and systemic health, with larger benefits for those actively pushing their physical and cognitive limits. The conversation also covers the molecule's potential in skincare, combining ESS-60 with GHK copper peptides for enhanced collagen production and wrinkle reduction.

Outlines

Part 1: Discovery, Science, and Properties

Part 2: Longevity, Antioxidants, and Biological Impact

Part 3: Industry Evolution and Research

Part 4: Performance, Stacking, and Formulations

Part 5: Optimization and Final Outlook

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