22 Jan 2026
1h 13m

This Brain Trick Feels Like Cheating (Do THIS) : 1402

Podcast cover

The Human Upgrade: Biohacking for Longevity & Performance

The discussion centers on optimizing brain health by targeting mitochondrial function and the brain's immune system. Neurologist Dr. David Perlmutter joins the conversation to discuss how microglial cells, the brain's immune cells, can shift from supportive (M2) to destructive (M1) based on metabolic factors. They explore interventions like GLP-1 agonists, hyperbaric oxygen, and even lifestyle choices that can nudge microglia back to a supportive state. Dr. Perlmutter shares insights on the role of inflammation, the impact of diet on prefrontal cortex function, and the potential for microdosing pharmaceuticals to enhance metabolic health. The conversation also touches on the interconnectedness of mitochondria throughout the body and the potential for quantum communication between them.

Outlines

Part 1: Brain Health, Metabolism, and Microglia

Part 2: Environmental Toxins and Pharmaceutical Interventions

Part 3: Lifestyle Strategies and Metabolic Behavior

Part 4: Biofields, Consciousness, and Spiritual Healing

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