"What’s good for the heart is good for the brain." Can better cholesterol management in midlife actually lower your patient’s risk of Alzheimer’s disease?

In this episode, I’m joined by returning guest Josh Wageman, PhD, PA-C, a clinical lipid specialist who studied cholesterol disturbances in Alzheimer’s disease. Together, we unpack how cholesterol, APOB, APOE4, insulin resistance, and statins intersect with Alzheimer’s disease and cognitive decline, and what clinicians can do now to protect brain health long before symptoms appear.

Plus, a peek at emerging therapies (including GLP-1 receptor agonists and lipid-centric approaches) and how a metabolic lens is reshaping future Alzheimer’s treatment.

Resources Mentioned:

Josh's New Book

117 | What’s the Best Diet to Lower Cholesterol?

111 | HDL = Good, LDL = Bad? It’s Not That Simple.

80 | The MIND Diet: What To Eat For Brain Health

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Disclaimer: This podcast is a collection of ideas, strategies, and opinions of the author(s). Its goal is to provide useful information on each of the topics shared within. It is not intended to provide medical, health, or professional consultation or to diagnosis-specific weight or feeding challenges. The author(s) advises the reader to always consult with appropriate health, medical, and professional consultants for support for individual children and family situations. The author(s) do not take responsibility for the personal or other risks, loss, or liability incurred as a direct or indirect consequence of the application or use of information provided. All opinions stated in this podcast are my own and do not reflect the opinions of my employer.

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137 | Cholesterol in the Brain: Connecting Heart Health and Alzheimer’s