02 Dec 2025
42m

Ep 77: Anthropic’s Dianne Na Penn on Opus 4.5, Rethinking Model Scaffolding & Safety as a Competitive Advantage

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Unsupervised Learning with Jacob Effron

In this episode of Unsupervised Learning, Jacob Effron interviews Dianne Na Penn, Head of Product for Research at Anthropic, about the new Opus 4.5 model. They discuss the model's improved capabilities, including instruction following, coding, and memory, as well as its applications in areas like Excel and PowerPoint. Dianne shares insights into Anthropic's research process, the importance of safety in product development, and the company's focus on business use cases. They explore the potential of computer use and long-running AI agents, and the need for better evaluations to measure the quality of AI judgment. Dianne also touches on Anthropic's culture, key decision points in their journey, and the benefits of aligned AI models.

Outlines

Part 1: Introduction and Capabilities

Part 2: Market Education and Model Improvements

Part 3: Future Directions and Evaluations

Part 4: Culture, Decisions, and Future Outlook

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