July 2025; papers of the month

Emergency medicine practitioners evaluate three clinical studies to inform resuscitation and acute care practices. A systematic review of post-cardiac arrest management indicates that noradrenaline may lower the odds of recurrent arrest compared to adrenaline, though current evidence remains primarily observational and requires further validation. In pediatric status epilepticus, adding ketamine to midazolam significantly improves seizure cessation rates compared to midazolam alone, especially in cases lasting over 30 minutes, suggesting a potential shift in first-line treatment strategies. Regarding acute migraine management, intramuscular metoclopramide appears to reduce emergency department length of stay compared to intravenous administration, likely by streamlining patient throughput without sacrificing analgesic efficacy. These findings highlight the need for larger, randomized controlled trials to refine clinical protocols and improve patient-centered outcomes across diverse emergency settings.