Today, I’m joined by the pioneering duo behind Young Goose and two of the earliest voices to bring longevity science into the world of skincare. Amitay comes from the red light therapy space, while Anastasia’s background is rooted in cancer research and regenerative medicine—together, their bold thesis is that youthful skin is not just about appearance, it’s an energy state.

Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you’re an existing customer.

Episode Timestamps:

Skin longevity: appearance vs resilience vs long-term health ... 00:06:42

Why topical NAD matters for skin ... 00:14:07

Importance and decline of NAD as we age ... 00:18:26

Why spermidine was added to skincare ... 00:21:00

How spermidine drives autophagy and hydration ... 00:25:43

Spermidine’s impact on wrinkles and skin barrier ... 00:29:06

Longevity skincare vs traditional approaches ... 00:31:18

Methylene blue’s unique benefits and formulation ... 00:34:04

Methylene blue vs other antioxidants ... 00:36:16

Methylene blue’s role in recovery and protection ... 00:46:13

Platelet-derived, quantified exosomes explained ... 00:51:44

How to layer exosomes in your skincare ... 01:01:13

Biggest myths in skin longevity ... 01:02:41

Does topical NAD and spermidine really work? ... 01:08:28

Where to start with Young Goose products ... 01:19:33

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#381: Better Than Lasers: NAD+, Spermidine, and Methylene Blue for Youthful Skin | Amitay Eshel and Anastasia Khodzhaeva

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#381: Better Than Lasers: NAD+, Spermidine, and Methylene Blue for Youthful Skin | Amitay Eshel and Anastasia Khodzhaeva