In this interview podcast, the host and Dr. Ben Bikman discuss insulin resistance as a key contributor to chronic diseases, often developing silently for years. Dr. Bikman explains how insulin resistance remains hidden until advanced stages due to the glucocentric paradigm in modern clinical care, and he suggests early detection through simple tests and actionable steps to reverse it. The conversation covers insulin's broader physiological roles beyond blood glucose, its influence on fat storage, appetite regulation, inflammation, and chronic disease. They also discuss macronutrients and insulin sensitivity, meal timing, the dangers of visceral fat, lifestyle factors, and the emerging use of GLP-1 agonist medications, as well as practical strategies for improving insulin sensitivity.
Outlines
Part 1: Introduction to Insulin Resistance
Part 2: Diet, Insulin, and Metabolic Health
Part 3: Strategies for Insulin Sensitivity
Part 4: Fat Cells and Insulin Resistance
Part 5: GLP-1 Agonists
Part 6: Insulin, Glucose, and Aging
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