YouTube23 Jun 2025
1h 51m

Control Your Vagus Nerve to Improve Mood, Alertness & Neuroplasticity

Podcast cover

Andrew Huberman

In this episode of the Huberman Lab Podcast, Andrew Huberman explores the vagus nerve (cranial nerve 10), detailing its extensive connections between the brain and body and its role as both a sensory and motor pathway. He emphasizes the vagus nerve's actionability, providing science-backed tools to control it for improved alertness, relaxation, mood, learning, heart rate variability and overall health. Huberman discusses practical techniques such as deliberate breathwork (physiological sighs and extended exhales), mechanical activation through neck stretches and humming, and the importance of exercise in stimulating the vagus nerve to enhance brain function and neuroplasticity. He also delves into the gut-brain connection, explaining how maintaining a healthy gut microbiome and adequate tryptophan intake can positively influence serotonin levels in the brain via vagal signaling, impacting mood and overall well-being.

Outlines

Part 1: Introduction and Anatomy

Part 2: Activation and Autoregulation

Part 3: Alertness and Neuroplasticity

Part 4: Serotonin and Calming

Part 5: Summary and Support

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