#2338 - Beth Shapiro | The Joe Rogan Experience

In this episode of the Joe Rogan Experience, Joe interviews Beth Shapiro, a paleogeneticist and chief science officer at Colossal. They discuss ancient DNA, the process of extracting it, and the challenges and controversies surrounding the field, including gatekeeping in academia. Beth recounts her journey from broadcast journalism to science, her experiences in Siberia studying ancient DNA, and Colossal's work on de-extinction, specifically the dire wolf project. They explore the ethical implications of de-extinction, the impact of invasive species, and the potential for genetic rescue in conservation efforts. They also touch on various topics such as the history of humans, the nature of species, and the potential for genetic engineering to cure diseases.

Outlines

Part 1: Introduction and Early Adventures

Part 2: Ancient DNA and De-extinction

Part 3: Colossal's Projects and Ethical Considerations

Part 4: Species, Mammoths, and Scientific Arrogance

Part 5: Recent Discoveries and Colossal's Future

Part 6: Animals, Domestication, and Gene Editing

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#2338 - Beth Shapiro

The Joe Rogan Experience

Part 1: Introduction and Early Adventures

Introduction to Ancient DNA and Beth Shapiro's Career Transition

Discovering Ancient DNA and First Experiences in Siberia

Mosquitoes in Siberia and a Frustrating Expedition in Taimyr

Encounter with the Dolgan People and the French Couple's Cheese

Reflections on Indigenous Cultures and Discoveries in the Amazon

Part 2: Ancient DNA and De-extinction

From Ancient DNA to Colossal: The Jurassic Park Question and DNA Contamination

Clean Labs, Neanderthal Genomes, and Komodo Dragon Encounters

Giraffe Intelligence, Video Games, and the Ethics of De-extinction

Part 3: Colossal's Projects and Ethical Considerations

Invasive Species, Genetic Rescue, and the Red Wolf Project

The Hippo Ranching Plan and Pablo Escobar's Hippos

Wild Boars, the Hippo Bill, and the Wolf Reintroduction in Colorado

Ballot Box Biology, the Dire Wolf Project, and Polar Bear Hybrids

Part 4: Species, Mammoths, and Scientific Arrogance

Species Concepts, Bison Skulls, and Dawson City

Mammoth Teeth, Thomas Jefferson's Mammoth Obsession, and the Theory of American Degeneracy

The Arrogance of Science and the Importance of Ancient DNA

Beefalo Scams and the Search for the Genes that Make Us Human

Part 5: Recent Discoveries and Colossal's Future

Ancient DNA from Sediments and the Tridactyl Skeletons of Peru

Colossal's Future Plans and the Negativity of Haters

Playing God, Genetic Rescue, and the Woolly Mammoth

The Short-Faced Bear, the Irish Elk, and the California Golden Bear

Part 6: Animals, Domestication, and Gene Editing

Monarch, the California Golden Bear, and Encounters with Jaguars

Bigfoot Sightings and the Importance of Wind

Dog Domestication and the Grey Wolf

Grafting Plants and Autonomous Coal Production

Chinese Scientists and the Long Game

The Ethical Concerns of Gene Editing

#2338 - Beth Shapiro

The Joe Rogan Experience

Part 1: Introduction and Early Adventures

00:11Introduction to Ancient DNA and Beth Shapiro's Career Transition

Introduction to Ancient DNA and Beth Shapiro's Career Transition

05:37Discovering Ancient DNA and First Experiences in Siberia

Discovering Ancient DNA and First Experiences in Siberia

10:40Mosquitoes in Siberia and a Frustrating Expedition in Taimyr

Mosquitoes in Siberia and a Frustrating Expedition in Taimyr

17:21Encounter with the Dolgan People and the French Couple's Cheese

Encounter with the Dolgan People and the French Couple's Cheese

23:04Reflections on Indigenous Cultures and Discoveries in the Amazon

Reflections on Indigenous Cultures and Discoveries in the Amazon

Part 2: Ancient DNA and De-extinction

29:58From Ancient DNA to Colossal: The Jurassic Park Question and DNA Contamination

From Ancient DNA to Colossal: The Jurassic Park Question and DNA Contamination

37:05Clean Labs, Neanderthal Genomes, and Komodo Dragon Encounters

Clean Labs, Neanderthal Genomes, and Komodo Dragon Encounters

45:02Giraffe Intelligence, Video Games, and the Ethics of De-extinction

Giraffe Intelligence, Video Games, and the Ethics of De-extinction

Part 3: Colossal's Projects and Ethical Considerations

53:01Invasive Species, Genetic Rescue, and the Red Wolf Project

Invasive Species, Genetic Rescue, and the Red Wolf Project

1:02:03The Hippo Ranching Plan and Pablo Escobar's Hippos

The Hippo Ranching Plan and Pablo Escobar's Hippos

1:09:02Wild Boars, the Hippo Bill, and the Wolf Reintroduction in Colorado

Wild Boars, the Hippo Bill, and the Wolf Reintroduction in Colorado

1:17:20Ballot Box Biology, the Dire Wolf Project, and Polar Bear Hybrids

Ballot Box Biology, the Dire Wolf Project, and Polar Bear Hybrids

Part 4: Species, Mammoths, and Scientific Arrogance

1:25:34Species Concepts, Bison Skulls, and Dawson City

Species Concepts, Bison Skulls, and Dawson City

1:35:35Mammoth Teeth, Thomas Jefferson's Mammoth Obsession, and the Theory of American Degeneracy

Mammoth Teeth, Thomas Jefferson's Mammoth Obsession, and the Theory of American Degeneracy

1:41:11The Arrogance of Science and the Importance of Ancient DNA

The Arrogance of Science and the Importance of Ancient DNA

1:47:20Beefalo Scams and the Search for the Genes that Make Us Human

Beefalo Scams and the Search for the Genes that Make Us Human

Part 5: Recent Discoveries and Colossal's Future

1:55:06Ancient DNA from Sediments and the Tridactyl Skeletons of Peru

Ancient DNA from Sediments and the Tridactyl Skeletons of Peru

2:01:10Colossal's Future Plans and the Negativity of Haters

Colossal's Future Plans and the Negativity of Haters

2:08:20Playing God, Genetic Rescue, and the Woolly Mammoth

Playing God, Genetic Rescue, and the Woolly Mammoth

2:17:20The Short-Faced Bear, the Irish Elk, and the California Golden Bear

The Short-Faced Bear, the Irish Elk, and the California Golden Bear

Part 6: Animals, Domestication, and Gene Editing

2:25:04Monarch, the California Golden Bear, and Encounters with Jaguars

Monarch, the California Golden Bear, and Encounters with Jaguars

2:31:10Bigfoot Sightings and the Importance of Wind

Bigfoot Sightings and the Importance of Wind

2:37:07Dog Domestication and the Grey Wolf

Dog Domestication and the Grey Wolf

2:42:33Grafting Plants and Autonomous Coal Production

Grafting Plants and Autonomous Coal Production

2:50:30Chinese Scientists and the Long Game

Chinese Scientists and the Long Game

2:59:31The Ethical Concerns of Gene Editing

The Ethical Concerns of Gene Editing