461: How Bad Science Misled Alzheimer’s Research for Decades | Charles Piller

This episode of the Genius Life podcast interviews Charles Piller, an investigative reporter, about his book "Doctored," which exposes fraud in Alzheimer's research. The discussion covers Piller's discovery of manipulated images in seminal Alzheimer's studies, the impact of this fraud on funding and drug development, and the resulting crisis of confidence in the amyloid hypothesis. Piller details the consequences for researchers involved, including the dismissal of a leading NIH scientist. The interview also explores alternative hypotheses for Alzheimer's, such as the role of latent infections and the potential of GLP-1 agonist drugs, while emphasizing the importance of lifestyle choices in mitigating risk. Listeners gain insight into the complexities of Alzheimer's research and the need for greater transparency and rigor in scientific studies.