On this week's podcast, Brad Marshall, evolutionary biologist, talks with Paul about how signaling to our body that winter is coming is not advantageous for humans and why humans may want to stop consuming olive oil. They do a deep dive into the human metabolism, what European diets are truly like, and touch on other kinds of oils & fats as well.

00:00:00 Podcast begins

00:02:50 Brad’s weight loss journey

00:10:50 The human metabolism

00:15:10 How olive oil makes us fat

00:34:24 Deep dive into European diets

00:48:50 PREDIMED trial comparing different types of olive oil

00:51:05 De novo lipogenesis (DNL)

00:53:50 What happens when humans eat canola oil

00:59:20 A story about the Inuit & long-term ketosis

01:07:20 Takeaways about olive oil

Connect with Brad:

https://www.youtube.com/@fireinabottle3410

References:

Diabetes prevalence, 2021: https://ourworldindata.org/grapher/diabetes-prevalence

Trends of overweight, obesity and anthropometric measurements among the adult population in Italy: The CUORE Project health examination surveys 1998, 2008, and 2018: https://journals.plos.org/plosone/article/figure?id=10.1371/journal.pone.0264778.g004

OBESITY AMONG CHILDREN IN EUROPE: https://landgeist.com/2023/02/18/obesity-among-children-in-europe/

Modeling NAFLD disease burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016-2030: https://pubmed.ncbi.nlm.nih.gov/29886156/

Effects of free omega-3 carboxylic acids and fenofibrate on liver fat content in patients with hypertriglyceridemia and non-alcoholic fatty liver disease: A double-blind, randomized, placebo-controlled study: https://www.lipidjournal.com/article/S1933-2874(18)30362-3/fulltext

Quality of Dietary Fat Intake and Body Weight and Obesity in a Mediterranean Population: Secondary Analyses within the PREDIMED Trial: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315420/

244. Longevity Alert: The Dark Side of Olive Oil Revealed with Brad Marshall

Paul Saladino MD podcast

244. Longevity Alert: The Dark Side of Olive Oil Revealed with Brad Marshall