#312 - A masterclass in lactate: Its critical role as metabolic fuel, implications for diseases, and therapeutic potential from cancer to brain health and beyond | George A. Brooks, Ph.D.

This podcast episode reconstructs our understanding of lactate, challenging century-old misconceptions established by Otto Meyerhoff and presenting it as a critical energy source for the body rather than a mere byproduct of anaerobic metabolism. Through discussions on lactate's roles in various physiological and pathological contexts, including energy production, brain injury recovery, appetite regulation, and even cancer progression, the hosts reveal lactate's multifaceted contributions to human health, urging listeners to rethink its significance in metabolism.