We are living through one of the most significant shifts in medicine in generations, and most people don’t fully understand what it means. Dr. Christle Guevarra joins me to zoom out on the entire GLP-1 landscape; from the drug’s origins as a modest diabetes treatment in 2005 to today’s third-generation medications still moving through clinical trials, and what all of it means for the future of obesity, performance, and longevity.

🙌Thank you to our sponsors:

🌍 Cozy Earth - Go to https://bit.ly/4teXQhz for up to 20% off!

🤍 Timeline - Get 20% off your Mitopure order at https://bit.ly/48NFRX2

🚲 Carol Bike - Visit https://bit.ly/4tg4cxa and use code LYON for $100 off your CAROL Bike

Explore More from Dr. Gabrielle Lyon:

Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.com

Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/

Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/

Connect with Dr. Christle Guevarra

YouTube: https://bit.ly/4vDMVQa

Instagram: https://bit.ly/4mxnfAc

Get Dr. Christle Guevarra’s book, “Bodybuilding Anatomy”: https://bit.ly/3ODIDYd

📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:

YouTube: https://bit.ly/4boCFC3

Spotify: https://bit.ly/4cWTbLG

📱Connect with Dr. Gabrielle Lyon:

Instagram: https://bit.ly/4uk9adc

TikTok: https://bit.ly/3OFK3kJ

X.com: https://bit.ly/4l3YlaX

Facebook: https://bit.ly/3MBrJso

⏰Timestamps:

00:00 Intro of Show

07:27 Changes in the Fat Loss Landscape

12:22 Engagement in Competitive Powerlifting

17:00 Perspectives on GLP-1 Medication

31:01 Perimenopause Journey

32:02 Topamax

33:42 Urosepsis

35:03 Weight Loss Programming

36:48 Patients’ Decision to Take GLP-1

41:19 Risks and Effects on Taking GLP-1

41:57 Pancreatitis

45:30 Fen-Phen (Fenfluramine/phentermine” “Ephedra

50:22 Who Should Not Take GLP-1?

53:40 Proper Nutrition to Support Taking GLP-1

57:40 Recommendation for the New Dietary Guidelines

1:04:21 Residency and Sports Medicine Fellowship

1:06:15 Are Athletes Recommended to Take GLP-1?

1:13:26 Lack of Randomized, Controlled Trials for Peptides

1:15:30 Key Take-away’s from Dr. Christle

1:20:20 Should Women Weigh Themselves?

1:26:16 Should Women Lift Weights?

1:27:04 What’s Next for Dr. Christle?

‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

This episode includes paid sponsorships.

GLP-1 Side Effects, Risks, And Who Should Actually Be Using It | Dr. Christle Guevarra

The Dr. Gabrielle Lyon Show