Anglerfish, Gila Monsters, and the Origin of Weight Loss Drugs

This podcast episode explores the fascinating history of weight loss drugs, tracing their origins from deep sea fish and venomous lizards. In the 1980s, the discovery of GLP-1 in anglerfish and GLP-1 mimicking hormones in Gila monster venom paved the way for today's highly effective treatments. Researchers overcame skepticism and safety concerns to develop numerous GLP-1 receptor agonist drugs, including Ozempic and Wegovy.

Outlines

Sign in to continue reading, translating and more.

Continue

Motley Fool Money

The Origins of Weight Loss Drugs: From Anglerfish to Venomous Lizards

GLP-1 Discovery: From Recombinant DNA to Animal Venoms

The Gila Monster Venom: A Key to Unlocking Weight Loss Drugs

Gila Monsters and the Development of Diabetes Drugs

Gila Monster Venom Drug: Early Research Side Effects and Long-Term Safety Concerns

Ozempic's Side Effects: Long-Term Data vs. Expanded Population

Anglerfish, Gila Monsters, and the Origin of Weight Loss Drugs

Motley Fool Money

00:01The Origins of Weight Loss Drugs: From Anglerfish to Venomous Lizards

The Origins of Weight Loss Drugs: From Anglerfish to Venomous Lizards

03:41GLP-1 Discovery: From Recombinant DNA to Animal Venoms

GLP-1 Discovery: From Recombinant DNA to Animal Venoms

07:41The Gila Monster Venom: A Key to Unlocking Weight Loss Drugs

The Gila Monster Venom: A Key to Unlocking Weight Loss Drugs

11:28Gila Monsters and the Development of Diabetes Drugs

Gila Monsters and the Development of Diabetes Drugs

15:05Gila Monster Venom Drug: Early Research Side Effects and Long-Term Safety Concerns

Gila Monster Venom Drug: Early Research Side Effects and Long-Term Safety Concerns

17:17Ozempic's Side Effects: Long-Term Data vs. Expanded Population

Ozempic's Side Effects: Long-Term Data vs. Expanded Population