This podcast episode explores the fascinating history of weight loss drugs, tracing their origins from deep sea fish and venomous lizards. In the 1980s, the discovery of GLP-1 in anglerfish and GLP-1 mimicking hormones in Gila monster venom paved the way for today's highly effective treatments. Researchers overcame skepticism and safety concerns to develop numerous GLP-1 receptor agonist drugs, including Ozempic and Wegovy.