Infections in Older Adults

Infections in older adults frequently present atypically, manifesting as confusion, fatigue, or functional decline rather than classic symptoms like fever or cough. This diagnostic challenge necessitates a high index of suspicion, as infections account for over 13% of emergency department visits in this population. Pneumonia remains the primary cause of infection-related mortality, requiring clinicians to look beyond the classic triad and consider tachypnea as a sensitive indicator. Over-diagnosis of urinary tract infections remains a significant issue; distinguishing between symptomatic infections and asymptomatic bacteriuria is critical to curbing antibiotic overuse and preventing *Clostridioides difficile* infections. Furthermore, skin and soft tissue infections demand careful monitoring, as failure to improve warrants immediate investigation for necrotizing fasciitis. Emergency physician Danya Khoujah emphasizes that clinical gestalt and thorough patient assessment are essential for navigating these complex geriatric presentations and ensuring appropriate, evidence-based management.