Dr. Tony Wyss-Coray, a neurology professor at Stanford, joins Andrew Huberman to discuss the science of organ rejuvenation, focusing on factors in young blood that can reverse aging. The conversation explores experiments involving parabiosis, where connecting the circulatory systems of young and old mice led to improved cognition and tissue regeneration in the older mice. They discuss human trials involving plasma exchange and the identification of specific proteins, such as GDF11 and Clusterin, that may contribute to these rejuvenating effects. Wyss-Coray highlights the concept of "organ clocks," where individual organs age at different rates, and introduces Vero Biosciences, a company aiming to assess and potentially delay organ aging. The discussion also covers lifestyle factors, exercise, and future directions for research in the anti-aging field.
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