The podcast explores the history of scientific discoveries that faced initial ridicule, using Matt Kaplan's book, "I Told You So," as a guide. It highlights how scientists like Joseph Lister and Oliver Wendell Holmes were attacked for their groundbreaking work on antiseptic surgery and puerperal fever prevention, respectively. The discussion reveals that personal clashes and resistance to change often stifled progress, leading to unnecessary deaths. The conversation touches on the challenges faced by Kati Kariko in mRNA research and the negative impact of social media on scientific discourse. The podcast further examines the science behind kissing, including its cultural variations, potential origins in breastfeeding and pre-mastication, and the exchange of microbes.
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