This Huberman Lab podcast episode interviews Dr. Rhonda Patrick about optimizing brain and body health through micronutrients. The discussion begins with an overview of Dr. Patrick's work and then delves into the benefits of various micronutrients, including sulforaphane (found in broccoli sprouts and activated by mustard seed powder), omega-3 fatty acids (EPA and DHA, with a focus on bioavailability and dosage), and vitamin D3 (highlighting the importance of testing levels and sun exposure). Dr. Patrick also discusses the benefits of cold and heat exposure, emphasizing the importance of "intermittent challenge" for activating stress response pathways and improving health markers. Listeners gain actionable advice on supplementation, diet, and lifestyle choices to improve their health.