In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the October 2025 Emergency Medicine Practice article, Emergency Department Evaluation and Management of Patients With Adrenal Insufficiency

Introduction

Article Overview

Clinical Context & Epidemiology

Pathophysiology

Differential Diagnosis

Overlap with other diseases (infections, autoimmune, endocrine, psychiatric, cardiac, GI, etc.)
Importance of considering adrenal crisis in complex cases

Prehospital Care

Emergency Department Evaluation

Recognizing symptoms and prioritizing care
Role of EMR and clinical decision support
Key history and risk factors (medications, steroid use, opioid use, comorbidities)

Physical Examination

Diagnostic Workup

Treatment

Special Populations

Common Pitfalls & Takeaways

ClosingSummary and final thoughts

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Adrenal Insufficiency

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