Dr. Julia Linke (University of Mainz, Germany) joins AJP Audio to discuss the use of neural efficiency, a measure of brain activity, as a potential biomarker in the treatment of children with anxiety disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins the podcast to put the rest of the issue into context.

00:31 Linke interview
02:15 State or a trait?
04:15 Neural efficiency and CBT
05:22 Potential as a biomarker
07:08 Patient-rated and parent-rated measures of anxiety
08:16 Immediate clinical implications
09:50 Limitations
10:43 Future directions of research
11:44 Kalin interview
11:50 Linke et al.
15:16 Mallard et al.
18:11 Naples et al.
21:44 Mac Giollabhui et al.

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January 2026: Reduced Threat-Related Neural Efficiency: A Possible Biomarker for Pediatric Anxiety Disorders

American Journal of Psychiatry Audio