What it takes to be “Young Forever!” | Mark Hyman : 1385

In this episode of The Human Upgrade, Dave Asprey interviews Dr. Mark Hyman about his new book, "Young Forever," which explores the science of longevity and how to reverse biological aging. They discuss the hallmarks of aging, including deregulated nutrient sensing, insulin signaling, mTOR, AMPK, and sirtuins, and how these pathways can be influenced through lifestyle, diet, supplements, and certain medications. They delve into the controversies around metformin and Ozempic, emphasizing the importance of metabolic flexibility, muscle mass, and addressing the root causes of inflammation. Hyman shares a patient case study illustrating the power of diet in reversing chronic diseases and advocates for a shift from "anti-aging" to "healthy aging," focusing on optimizing health and function as we age.