In this episode of the Vitality Vision podcast, host Greg Bennett, along with Barry Miller and David Vogel, delve into the limitations of using A1C levels alone to determine diabetes risk. They analyze data from a UK biobank, revealing that individuals with the same A1C score of 5.7 can have vastly different risks of developing diabetes based on other biomarkers. The discussion highlights key predictors beyond A1C, such as BMI, SHBG, HDL, triglycerides, and CRP, emphasizing the importance of a holistic approach to assessing metabolic health. They also discuss the influence of genetics on diabetes risk, noting that while genetics play a role, lifestyle and metabolic scores are critical factors in determining outcomes, encouraging listeners to take proactive steps towards managing their health regardless of genetic predispositions.
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