This podcast episode delves into the critical issue of antifungal resistance, exploring its impact on patient outcomes and healthcare systems. It discusses the types of antifungal resistance, detection methods, and mechanisms, emphasizing the consequences and challenges it poses, particularly in candida infections. The episode concludes with a review of antifungal stewardship, global guidelines, promising new antifungals, and the significance of access to diagnostics and treatment tools worldwide. By understanding the evolving landscape of antifungal resistance, healthcare professionals can optimize treatments and improve patient outcomes.