In this interview, Sarah Ann Macklin speaks with exercise physiologist Inigo San Millan about mitochondrial health, its importance for overall well-being and longevity, and how to measure it. They discuss the limitations of VO2 max as a sole indicator of fitness, the significance of lactate as a biomarker, and the benefits of Zone 2 training for improving mitochondrial function and metabolic flexibility. San Millan emphasizes the role of exercise, particularly a balanced approach of Zone 2 and high-intensity training, over nutrition for enhancing mitochondrial health. The conversation also covers the implications of mitochondrial dysfunction in diseases like Alzheimer's and type 2 diabetes, and the importance of lifestyle factors like sleep and stress management.
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