In this episode of the Huberman Lab podcast, Dr. Andrew Huberman interviews Dr. David Fajgenbaum, a professor of translational medicine, about his work on finding new uses for existing drugs to treat rare and common diseases. Dr. Fajgenbaum shares his personal near-death experience with Castleman's disease and how it motivated him to start Every Cure, a non-profit dedicated to finding treatments for diseases that the medical field has deemed untreatable. The discussion covers the limitations of the current drug development system, the potential of already approved drugs to impact multiple pathways in the body, and examples of drugs with surprising benefits beyond their primary use. They also discuss the importance of patient agency, accessing expert knowledge, and the need for better databases to connect patients with potential treatments.
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