#370 - AMA #76: Peter evaluates longevity drugs, aspirin for CVD, and strategies to improve muscle mass — promising, proven, fuzzy, noise, or nonsense?

In this episode of "The Drive," Peter Attia and his co-host engage in an "Ask Me Anything" (AMA) session, addressing listener questions across three main categories. They use a "proven, promising, fuzzy, noise, nonsense" scale to evaluate various interventions. The discussion covers drugs for geroprotection, including GLP-1 agonists, SGLT2 inhibitors, methylene blue, and telomere-lengthening supplements, assessing their potential anti-aging benefits beyond metabolic effects. They also examine the role of low-dose aspirin in cardiovascular disease prevention, weighing its risks and rewards. Finally, they delve into interventions for improving muscle mass, focusing on protein intake and follistatin gene therapy, evaluating the evidence and addressing common concerns about protein consumption and cancer.