This Mea Culpa special episode of The Studies Show covers corrections, retractions, and oversights from previous episodes. It acknowledges mistakes made regarding statistical significance, the colon and large intestine distinction, cancer prevalence, and the cause of muscle pain during exercise. The episode also tackles criticisms received, discussing topics such as depression, social media's effects on it, and the reading wars. The hosts emphasize their commitment to accuracy and openness to corrections, highlighting the importance of evidence-based discussions in understanding complex issues.