This "Best Of" episode of The Knowledge Project podcast compiles key insights from interviews conducted throughout 2022, focusing on practical strategies for personal and professional improvement. The episode features excerpts from conversations with experts on happiness, leadership, decision-making, and aging, offering evidence-based approaches and actionable advice. For example, Laurie Santos discusses evidence-based approaches to happiness, including gratitude practices and negative visualization. Listeners gain insights into improving well-being, building resilience, and making better decisions, ultimately aiming to enhance their lives in 2023. The episode concludes with reflections on gratitude and prioritizing what truly matters in life.