This podcast episode discusses various supplements and drugs that are commonly believed to increase lifespan. The speaker specifically talks about resveratrol, NAD precursors such as NR and NMN, NAD infusions, metformin, and rapamycin. Although there is no concrete evidence to support the idea that these interventions can actually extend lifespan in humans, there is ongoing interest in increasing NAD levels and further research is needed in the field of longevity and supplementation.
Takeaways
• Resveratrol gained attention in the past for its potential to increase lifespan, but most of the thinking around its longevity effects has been debunked.
• Grape seed extract, containing resveratrol, may have positive effects on vascular function and blood flow, but there is little direct evidence of its ability to increase lifespan.
• NAD precursors, such as NR and NMN, are often associated with increasing lifespan, but there is currently no data substantiating this claim.
• NAD infusions are becoming more common, but the discomfort associated with the procedure should be taken into consideration.
• Metformin and berberine are often used to lower blood glucose levels and impact the mTOR pathway, but there is no direct evidence linking these interventions to increased lifespan in humans.
• Rapamycin is being studied for its potential to extend lifespan, but there is currently insufficient data to support its use.
• Supplements should be viewed as enhancements rather than the foundation of mental and physical health, and lifestyle factors play a crucial role in overall well-being.
• Further scientific research and discussion are needed to fully understand the effects of supplements and drugs on longevity.
