In this episode of The Internet Book of Critical Care Podcast, Josh and Adam discuss the diagnosis and management of meningitis and encephalitis in critically ill patients. They cover when to suspect a CNS infection, emphasizing the importance of considering it in patients with neurological symptoms and signs of infection. The discussion includes the initial steps of management such as droplet precautions, empiric steroid and antibiotic therapy, and airway management, as well as the importance of cerebral perfusion pressure. They delve into the nuances of lumbar puncture, including when to perform a CT scan beforehand, how to interpret CSF results, and the utility of measuring opening pressure. The hosts also discuss antibiotic regimens based on CSF analysis, management of fever and seizures, the role of MRI, and considerations for CSF drainage in patients with elevated ICP.
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