IBCC Episode 49 - Septic Shock

In this episode of The Internet Book of Critical Care Podcast, Josh and Adam delve into the complexities of septic shock management, emphasizing the variability in treatment approaches among intensivists. They critique the Surviving Sepsis Campaign for its slow adaptation to new evidence and discuss the evolution of sepsis definitions, advocating for individualized patient assessment over rigid adherence to guidelines. The hosts cover key aspects such as the history of sepsis management, clinical presentations, sepsis mimics, source evaluation, vasopressor selection, antibiotic use, source control, and fluid resuscitation. They also explore controversial topics like metabolic resuscitation with vitamin C and the role of endpoints in guiding resuscitation efforts, highlighting the importance of balancing evidence-based practices with clinical judgment.