In this episode of the Internet Book for Critical Care Podcast, Josh and Adam discuss pulmonary vasculitis and diffuse alveolar hemorrhage, focusing on definition, diagnosis, and treatment. They differentiate between pulmonary vasculitis and angiovasculitis, highlighting ANCA-associated vasculitides as the most common type. The discussion covers clinical presentations, including diffuse alveolar hemorrhage, renal failure, and pulmonary-renal syndrome, along with diagnostic labs and imaging. They delve into the differential diagnosis, treatment algorithms involving antibiotics, steroids, and immunosuppressants, and address the controversial use of plasmapheresis. The podcast concludes with pearls and pitfalls for managing these complex cases in the ICU.
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