#819: Rhonda Patrick, Ph.D. — Protocols for Fasting, Lowering Dementia Risk, Reversing Heart Aging, Using Sauna for Longevity (Hotter is Not Better), and a Few Supplements That Might Actually Matter

In this episode of The Tim Ferriss Show, Tim interviews Dr. Rhonda Patrick, a biomedical scientist, about various actionable strategies for improving healthspan and mitigating age-related diseases. They discuss interventions for aging parents, including supplements like multivitamins, omega-3s, and ubiquinol, as well as the benefits of exercise, specifically CrossFit. The conversation covers the importance of vitamin D, the impact of ApoE4 on omega-3 brain delivery, and the potential of sulforaphane for detoxification and tremor reduction. They delve into fasting, including intermittent fasting and extended water fasts, and the role of ketosis and autophagy in repair processes. The discussion also explores the benefits of VO2 max training, the impact of exercise on heart and brain aging, and the pervasive issue of microplastic exposure and mitigation strategies. Finally, they touch on the effects of alcohol on the brain and cancer risk, and the potential benefits of creatine and psilocybin.