Throughout the first half of 2025 I did a blinded experiment to see how low to moderate melatonin intake affects me. In this post I summarize my findings.

Tl;dr: In my blinded self-experiment on melatonin, conducted over n = 60 days and analyzed with hypothesize.io, I found significantly positive effects for time to fall asleep (averaging ~25 instead of ~35 minutes, p ~= 0.001) and feeling awake the following morning (5.74/10 instead of 4.95/10, p = 0.006; but: this effect only persisted for the lower of two dosages, and did not persist throughout the rest of the day; could well be a false positive, as I didn’t correct for multiple hypothesis testing) for a dosage as low as 0.15mg of melatonin, taken on average ~1h before going to bed.