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Introduction

We, the free world, as a society, should decide to invest in the development of technology for human germline genomic engineering.

To me, this claim speaks for itself. Who wouldn't want to massively decrease the risks of many diseases in their future children? Who wouldn't want to give their children strong and diverse capabilities, like creativity, problem solving ability, wisdom, and empathy?

If so many people want this technology, doesn't it stand to reason that our scientists and entrepreneurs would be highly motivated and enabled to develop it? But, well, they aren't yet.

So, even though the claim speaks for itself, we have to ask: What would it look like to have a world where humanity greatly benefits from germline genomic engineering? What broader vision does reprogenetic technology fit into?

Some reasons we should work out [...]

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Outline:

(00:18) Introduction

(02:14) Disclaimers

(02:51) What is emancipation?

(03:59) What is genomic emancipation?

(06:29) Emancipation from whom?

(06:43) Mother Nature

(07:54) The lesion

(09:53) Emancipation of whom?

(13:07) Emancipation by whom?

(13:47) Emancipation how?

(16:48) Emancipation to where?

(17:00) The bush

(18:58) Expansion

(21:54) Intelligence

(24:02) Equal opportunity

(24:18) Emancipation when?

(24:54) The urgent need for health

(25:19) The urgent need for human capacity

(26:28) Safety, efficacy, and societal consent

(28:08) Genomic engineering overhang

(30:22) The internet and human destiny

(34:18) Heal whats in front of you

(36:15) Buttressing emancipated humanity

(36:43) The infinite game

(38:33) Growing pains

(39:43) Habermas and multigenerational feedback

(41:41) Fukuyama and human dignity

(44:19) C.S. Lewis and the tyranny of one generation

(48:23) Sandel, May, Heidegger: the giftedness of being

(54:27) Palinsynopsis

(56:06) Conclusion

(56:17) Appendix: Is this eugenics?

(56:28) The substantive question

(57:05) The terminological question

(01:03:29) Appendix: Why envision genomic emancipation?

(01:04:30) Noticing major problems

(01:04:51) To be destroyed by true refutations

(01:06:31) To be sharpened by true criticisms

(01:08:10) To hold our intentions strongly

(01:08:18) To be defended against false refutations

(01:11:27) To be exerted to realize the good possible worlds

(01:13:11) To be spread and amplified

(01:13:45) Blunt-force responses

(01:16:27) Blunt-force responses are good

(01:17:29) The blunt-force response against germline genomic engineering

(01:19:35) Critiques of character and motivation

(01:26:03) Deference as a blunt-force response

(01:28:13) Appendix: The origins of souls

(01:28:19) Influences on a childs genome

(01:30:51) Why not just have the state enforce beneficial choices?

(01:32:59) Forms of parental care

(01:37:24) Non-separateness of parent and child

(01:41:38) Appendix: Intelligence

(01:46:08) Appendix: on safer-sooner reprogenetics

(01:46:14) Examples of how reprogenetics is safer if developed sooner

(01:49:06) The ramp-up of reprogenetic strength

(01:52:05) Acknowledgement

The original text contained 14 footnotes which were omitted from this narration.

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First published:
June 21st, 2025

Source:
https://www.lesswrong.com/posts/rdbqmyohYJwwxyeEt/genomic-emancipation

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Narrated by TYPE III AUDIO.

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Images from the article:

Hebrew text written in an ancient or traditional script style.

Classical painting showing Prometheus chained to rocks by Mother Nature.

Dr. Seuss-style illustrations showing whimsical creatures with curly designs in black, white, and color.

Gothic cathedral architectural drawing showing wooden flying buttress support structures.

A lone tree silhouetted against glowing clouds in a mountainous landscape.

Hebrew text shown in dark letters against a light background.

Simple black and white illustration of bird releasing colorful feathers into wind.

Artistic illustration showing steps of human development labeled with societal concepts.

Two comparative scatter plots showing diversity of cognitive capacities with/without genomic emancipation.

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Whimsical drawing of blue and green feathers flowing in curved patterns.

A diagram comparing populations with and without genomic emancipation, showing disease variations.

Flow diagram showing epigenomic and genomic engineering research pathways in reproductive biology. Divided into pink (epigenomic correctness) and blue (genomic vectoring) sections, with interconnected research steps, testing methods, and validation processes.

Comic strip showing dog character discussing biotech startup with increasing frustration.

Graph showing intelligence/capacity evolution across different revolutionary periods through time.

The graph plots

Two purple circular diagrams comparing populations with and without genomic emancipation, showing different characteristics.

Graph showing research progression from universities to corporations through

Graph showing genetic engineering techniques on feasibility vs. standard deviations scale.

The image displays various genetic modification approaches color-coded by epigenomic correction requirements, ranging from embryo selection (most feasible) to whole genome synthesis (most challenging).

Two comparative scatter plots showing diversity of cognitive capacities with/without genomic emancipation.

Dr. Seuss-style illustration of tree branches with whimsical hanging objects.

Cartoon character walking past pink wing-shaped trees in urban park.

Green and blue feathers swirling in an artistic Dr. Seuss-style illustration.

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Tide Pod detergent packet with purple and orange swirled colors.

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Comic strip showing Type A and B characters interacting over flowers and openness.

The green character (Type B) is calm while the pink character (Type A) becomes increasingly energetic, ending with them wearing a trophy labeled

Sailing ship beneath spectacular aurora-like lights and golden streaks in mountainous waters.

An illustration showing balancing scientific progress with ethical considerations in healthcare

This appears to be an illustration from a Dr. Seuss book, showing a whimsical mechanical contraption called the

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“Genomic emancipation” by TsviBT

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