This episode of Radiolab, part of a week dedicated to sharks, explores the surprising potential of shark antibodies in fighting human diseases like cancer. The story begins with a visit to a secret lab in Wisconsin where nurse sharks are being used to develop these antibodies. The discussion then delves into the evolution of immune systems, highlighting the unique ability of immune cells to create tailor-made antibodies. Scientists discovered that sharks, the oldest living creatures with a similar immune system to humans, possess unique, tiny, flexible antibodies that can access parts of cancer cells that human antibodies cannot. These shark antibodies have shown remarkable success in early experiments, eradicating tumors in mice without triggering an immune response, leading to further research into their potential to combat various diseases, including cancer, pain, and Alzheimer's.
