In this interview, Jack Altman interviews his brother, Sam Altman, about the future of AI, focusing on the medium term (5-10 years). They discuss AI's potential impact on software, science, and the physical world, including coding, scientific discovery, business creation, self-driving cars, and humanoid robots. Sam expresses surprise at the rapid progress in AI reasoning and believes AI will significantly accelerate scientific discovery, potentially leading to new physics and advancements in astrophysics. The conversation shifts to OpenAI's role, envisioning an AI companion that integrates into various aspects of life and the importance of the entire AI supply chain. They also touch on energy consumption, fusion power, space exploration, competition with Meta, and the balance between commercial and research aspects of OpenAI, ending with Sam's reflections on his role and the societal impact of AI.