This NPR News podcast, "Up First," presents three main stories: the military deployment in Los Angeles amidst anti-ICE protests and the concerns surrounding their role and coordination with local authorities; the economic impact of President Trump's immigration crackdown, which is driving some workers into hiding and affecting industries reliant on immigrant labor; and an appeal hearing for President Trump's criminal conviction related to hush money payments, focusing on the arguments being made and the likelihood of success. The podcast also includes segments promoting other NPR podcasts and fundraising for public media.