Steven Bartlett interviews Dr. Georgia Ede about a study on the ketogenic diet's effects on refractory mental illness. Dr. Ede explains the ketogenic diet's history, initially developed to treat seizures, and its mechanism of action by reducing inflammation, oxidative stress, and insulin resistance, thereby improving brain chemistry. The study, conducted by Dr. Albert Donat, involved 31 inpatients with treatment-resistant bipolar disorder, major depression, or schizophrenia. Remarkably, 43% achieved clinical remission, and 64% left the hospital on reduced medication, highlighting the potential benefits of the ketogenic diet for mental health, although the hospital setting is acknowledged as a confounding factor due to the level of supervision and support provided.
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