In this monologue, John Salmanton-Garcia, a postdoctoral researcher, shares interesting and concerning results regarding respiratory viral infections from the ESMED Global 2025. He highlights a Belgian study on wastewater surveillance showing year-round SARS-CoV-2 prevalence and pathogen competition between SARS-CoV-2, influenza, and RSV. He also discusses the potential reformulation of influenza vaccines due to the disappearance of the influenza B yamagata strain, based on Italian research. Furthermore, he presents findings on rhinovirus infections in younger adults from a Chinese study and a French report comparing respiratory viral infection distributions before and during the COVID-19 pandemic. He also summarizes a Danish case-control study on the health economics of RSV infections, and presents results from the EPICOVIDIHA registry on respiratory viral infections in hematological malignancy patients, noting the severity and mortality associated with less frequent viral pathogens.