In this special 10-year anniversary episode of Cortex, Myke and Grey reflect on the show's origins as a ten-episode pilot, its evolution, and its impact on their professional lives. They discuss the challenges of creating a non-news-driven show, the importance of editing, and memorable episodes like the AI and book club series. Grey announces he will be taking a sabbatical, and Myke will continue the show with guest interviews focused on workflows. They answer listener questions about the show's beginnings, the likelihood of lasting ten years, and the greatest challenges and gratifications of working together. They also delve into their experiences with RSI and the surprising benefits of weight training, as well as the ongoing debate about productivity optimization. The episode concludes with reflections on their work over the past decade, including shifts in the podcasting business, the move towards membership models, and personal growth.