In this episode of the "FYI: For Your Innovation" podcast, hosts Brett Winton and Nemo Despot interview Mike Nally, CEO, and Jason, CFO, of Generate Bio, an AI-driven drug discovery company. The discussion centers on Generate Bio's innovative approach to protein therapeutic engineering, contrasting it with traditional, stochastic methods. They delve into how Generate Bio utilizes structural biology, particularly Cryo-EM, and machine learning to accelerate drug development, reduce costs, and target previously "undruggable" diseases. The conversation explores the potential for AI to transform the pharmaceutical industry's economic structure, emphasizing the importance of data-driven models and strategic partnerships to overcome capital-intensive challenges and ultimately consolidate the fragmented drug development landscape.
