Rheumatoid arthritis, lupus, and Crohn’s disease are autoimmune diseases that share a lot of commonalities. This episode covers when and how they were first recognized and described.

Research:

Aceves-Avila, Francisco Javier et al. “The Antiquity of Rheumatoid Arthritis: A Reappraisal.” The Journal of Rheumatology 2001; 28:4.
Arnaud, Laurent et al. “The History of Lupus Throughout the Ages.” Journal of the American Academy of Dermatology. Volume 87, Issue 6, December 2022. https://www.sciencedirect.com/science/article/abs/pii/S0190962220307726
Barber, Megan R W et al. “Global epidemiology of systemic lupus erythematosus.” Nature reviews. Rheumatology vol. 17,9 (2021): 515-532. doi:10.1038/s41584-021-00668-1 Bornstein, Joseph E. and Randolph M. Steinhagen. “History of Crohn’s Disease.” From Crohn’s Disease: Basic Principles. Springer. 2015.
Crohn & Colitis Foundation. “IBD before the Foundation.” https://www.crohnscolitisfoundation.org/about/our-beginning
Entezami, Pouya et al. “Historical perspective on the etiology of rheumatoid arthritis.” Hand clinics vol. 27,1 (2011): 1-10. doi:10.1016/j.hcl.2010.09.
Geller, Stephen A. and Fernando P F de Camposc. “Crohn disease.” Autopsy Case Rep [Internet]. 2015; 5(2):5-8. http://dx.doi.org/10.4322/acr.2015.001
Hyndman, I.J. (2017), Rheumatoid arthritis: past, present and future approaches to treating the disease. Int J Rheum Dis, 20: 417-419. https://doi.org/10.1111/1756-185X.12823
Kirsner, J B. “Historical origins of current IBD concepts.” World journal of gastroenterology vol. 7,2 (2001): 175-84. doi:10.3748/wjg.v7.i2.175
Laberge, Monique, and Philip E. Koth. "Rheumatoid Arthritis." The Gale Encyclopedia of Medicine, edited by Jacqueline L. Longe, 6th ed., vol. 7, Gale, 2020, pp. 4474-4480. Gale In Context: Science, link.gale.com/apps/doc/CX7986601640/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=8b8ee977. Accessed 30 Apr. 2025.
Laurent Arnaud - I6 The history of lupus throughout the ages: Lupus Science & Medicine 2020;7:. https://doi.org/10.1136/lupus-2020-eurolupus.6
org. “The History of Lupus.” https://www.lupus.org/resources/the-history-of-lupus
Mandal, Dr. Ananya. “Rheumatoid Arthritis History.” News Medical. 7/7/2023. https://www.news-medical.net/health/Rheumatoid-Arthritis-History.aspx
Medical News Today. “The History of Rheumatoid Arthritis.” 5/2/2023. https://www.medicalnewstoday.com/articles/rheumatoid-arthritis-history
Michniacki, Thomas. “Crohn’s Disease: An Evolutionary History.” University of Michigan Library. 2006-05 http://hdl.handle.net/2027.42/96969
Potter, Brian. “The History of the Disease Called Lupus.” Journal of the History of Medicine and Allied Sciences , JANUARY 1993, Vol. 48, No. 1 (JANUARY 1993). Via JSTOR. http://www.jstor.com/stable/24622869
Sathiavageesan, Subrahmanian, and Suganya Rathnam. “The LE Cell-A Forgotten Entity.” Indian journal of nephrology vol. 31,1 (2021): 71-72. doi:10.4103/ijn.IJN_249_19
Scofield, R Hal, and James Oates. “The place of William Osler in the description of systemic lupus erythematosus.” The American journal of the medical sciences vol. 338,5 (2009): 409-12. doi:10.1097/MAJ.0b013e3181acbd71
"Systemic Lupus Erythematosus." National Institute of Arthritis and Musculoskeletal and Skin Diseases Pamphlets, National Institute of Arthritis and Musculoskeletal and Skin Diseases, 2001, p. 1. Gale Academic OneFile, link.gale.com/apps/doc/A79512544/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=534bac78. Accessed 30 Apr. 2025.
Thomas, Donald E. et al. “The first use of “lupus” as a disease.” Lupus. 2025, Vol. 34(1) 3–9.
Tish Davidson, and Rebecca J. Frey. "Crohn's Disease." The Gale Encyclopedia of Medicine, edited by Jacqueline L. Longe, 6th ed., vol. 2, Gale, 2020, pp. 1423-1427. Gale In Context: Science, link.gale.com/apps/doc/CX7986600509/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=2687d598. Accessed 30 Apr. 2025.
Van Hootegem, Phillippe. “Is Crohn’s A Rightly Used Eponym?” J Crohns Colitis. 2020 Jul 9;14(6):867-871. doi: 10.1093/ecco-jcc/jjz183.

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